Ethambutol is a drug used, alone or in combination with other drugs, to treat tuberculosis and other infections. It is sold under the trade names Myambutol (X-GEN Pharmaceuticals) and Servambutol (Sandoz). Although it is effective, it has several adverse side effects, such as vision, liver, and allergy problems.
L. L. Kiessling (University of Wisconsin鈥揗adison), in her聽Fred Kavli Innovations in Chemistry Lecture聽at the spring 2015 ACS National Meeting in Denver, described ethambutol as 鈥渁 not great drug鈥�. She advocated targeting microbial cell-surface carbohydrates to combat mycobacterial diseases. In particular, she suggested galactofuranoses as particularly attractive targets for protein antibiotics.
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