Strigol

February 16, 2016
I am named after a notorious predatory weed.
What molecule am I?
Image of Strigol 3D Image of Strigol

Strigol is a member of the strigolactone family of plant hormones that are potent root-germination stimulants for some parasitic plants (read 鈥渨eeds鈥�). Their function is to stimulate the growth of certain fungi that have a symbiotic relationship with the plants.

Strigol takes its name from the African predatory plant witchweed (Striga lutea Lour.), which can聽wipe out crops such as rice, sorghum, millet, and sugarcane. C. E. Cook at the Research Triangle Institute (NC) and colleagues first isolated it in 1966 from root exudates of cotton (Gossypium hirsutum L.). Six years later, same researchers . The naturally occurring (+)-enantiomer聽 by Charles J. Sih and co-workers at the University of Wisconsin (Madison) in 1976.

It wasn鈥檛 until 2015 that Peter McCourt and colleagues at the University of Toronto . The weed has exceptionally large strigolactone binding pockets, which allow it to 鈥渟niff out鈥� strigol and other strigolactones produced by the food crops. In this way, witchweed recruits symbiotic fungi from the crop plants and essentially starves them.

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