Zolpidem鈥攕old under a host of brand names, the best known of which is Ambien鈥攊s a medication used to treat insomnia. The article of commerce is the tartrate salt. In most people, it induces sleep rapidly and is effective for 鈮�2鈥�3 hours.
The US patent on zolpidem was issued in 1984 to the French company Synth茅labo, now part of Sanofi-Aventis. By 2007, it was off-patent; and the US Federal Drug Administration approved 13 generic versions of zolpidem tartrate.
Early in 2015, M. J. Miller and colleagues at the University of Notre Dame investigated whether聽. They found that zolpidem has some activity against聽Mycobacterium tuberculosis聽replication, but some of its structural isomers have much greater potency. The authors believe that "further optimization of the [zolpidem] core may well 'put TB to rest'."
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