EMBARGOED FOR RELEASE聽|聽April 07, 2013

Nobel laureates and their research teams at American Chemical 中国365bet中文官网 meeting

Note to journalists: Please report that this research was presented at a meeting of the American Chemical 中国365bet中文官网.

NEW ORLEANS, April 7, 2013 鈥� At least nine Nobel laureates have research that will be presented here this week during the 245th National Meeting & Exposition of the American Chemical 中国365bet中文官网, the world鈥檚 largest scientific society. Research from the laureates鈥� teams will be among almost 12,000 presentations during the event, expected to attract more than 14,000 scientists and others.

They are Robert H. Grubbs, Ph.D.; Richard R Schrock, Ph.D.; Brian K. Kobilka, Ph.D.; Robert J. Lefkowitz, Ph.D.; Ei-ichi Negishi, Ph.D.; George A. Olah, Ph.D.; Karl Barry Sharpless, Ph.D.; Ada Yonath, Ph.D.; and Ahmed Zewail, Ph.D.

Grubbs, who is with the California Institute of Technology, and Schrock, who is with the Massachusetts Institute of Technology, shared the with Yves Chauvin for the development of the 鈥渕etathesis method.鈥� That new way to make plastics, medicines and other products was an advance in 鈥済reen chemistry,鈥� because it reduces the production of potentially hazardous waste compared with other approaches.

Kobilka, who is with the Stanford University School of Medicine, and Lefkowitz, who is with the Howard Hughes Medical Institute and the Duke University Medical Center, shared the "for studies of G-protein-coupled receptors.鈥� Their research showed how these receptors work to sense the environment of the cell.

Negishi, the Herbert C. Brown Distinguished Professor of Organic Chemistry at Purdue University, shared the 鈥渇or palladium-catalyzed cross couplings in organic synthesis.鈥� This helped develop techniques to synthesize complex carbon molecules that have had an enormous impact on the manufacture of medicines and other products.

Olah, who is with the University of Southern California, won the for work on 鈥渃arbocations,鈥� charged molecules that were considered too unstable to study. Olah developed a way to isolate these molecules, which was useful in the oil and coal industries.

Sharpless, who is with The Scripps Research Institute, won the "for his work on chirally catalysed oxidation reactions." Sharpless worked on ways to synthesize just one of a set of 鈥渕irror鈥� image molecules. This work led to advances in drug development.

Yonath, who is with the Weizmann Institute of Science, shared the with Venkatraman Ramakrishnan and Thomas A. Steitz "for studies of the structure and function of the ribosome." They showed how the ribosome works at an atomic level to translate the information in DNA into proteins for life.

Zewail, who is with the California Institute of Technology, won the "for his studies of the transition states of chemical reactions using femtosecond spectroscopy." Zewail showed that it was possible to watch chemical reactions in 鈥渟low-motion鈥� using lasers to see how the molecules move.

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