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Note to journalists: Please report that this research will be presented at a meeting of the American Chemical 中国365bet中文官网.

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ORLANDO, Fla., April 2, 2019 鈥� Hundreds of everyday items, from furniture to cell phones to floor wax, contain organophosphate ester (OPE) flame retardants and plasticizers. Some of these semi-volatile compounds make their way into the air, onto surfaces and even inside our bodies, with uncertain health effects. Today, researchers report that hands play a central role in transferring OPEs and other flame retardants and plasticizers throughout the indoor environment.

The researchers will present their results today at the American Chemical 中国365bet中文官网 (ACS) Spring 2019 National Meeting & Exposition. ACS, the world鈥檚 largest scientific society, is holding the meeting here through Thursday. It features nearly 13,000 presentations on a wide range of science topics.

Increasingly, manufacturers have relied on OPEs to replace brominated flame retardants, some of which were banned or heavily restricted because of health concerns. However, a few recent epidemiological studies have linked the replacements themselves to adverse health effects. 鈥淭he toxicity of OPEs is not well understood,鈥� says Miriam Diamond, Ph.D., the project鈥檚 principal investigator. 鈥淪tudies are emerging that associate some OPEs with developmental effects in kids, fertility problems and possibly some types of cancer.鈥�

Previous studies have found relatively high concentrations of OPEs in indoor air and dust. However, the sources of these compounds were not always clear. 鈥淲e wondered if electronic devices, especially those that heat up during use, such as computers or printers, might be important sources of flame retardants and plasticizers,鈥� says Diamond, who is at the University of Toronto.

To find out, the researchers collected about 400 samples from the homes of 51 Canadian women enrolled in the Ontario Environment Health Study. These included urine samples and hand wipes from the women, surface wipes of their electronic devices, and air and dust samples. The team used mass spectrometry to determine the concentrations of 23 different OPEs in the wipes and eight OPE metabolites in urine.

To the researchers鈥� surprise, all indoor surfaces had similar chemical profiles, and larger electronic devices that heat up had no higher OPE levels than handheld devices. 鈥淲e went into this study expecting to find that surface wipes of different electronic devices would have elevated levels of one or a few flame retardants and plasticizers that were added to their casings during the manufacturing process,鈥� Diamond says. 鈥淚nstead, we found that most of the OPEs, and other flame retardants and plasticizers, were in most of the surface wipes, floor dust and on participants鈥� hands, as well as on the electronic devices. In other words, we found most of the chemicals everywhere.鈥�

Another unexpected result was that the level of OPEs on the surface wipes of cell phones predicted about 25 percent of the variability in urine levels of OPE metabolites 鈥撯€� suggesting that cell phones might be major sources of internalized OPEs, or perhaps they accumulate the compounds from other sources. When people use their cell phones (which most people touch hundreds or even thousands of times per day), they ingest the compounds or absorb them through their skin.

More recently, the researchers conducted a network analysis to find correlations among the chemical profiles they identified from all of the samples. They found that regardless of which group of chemicals they examined, hands were at the center of the network. 鈥淲e believe that hands are central to moving chemicals around the indoor environment,鈥� Diamond says. 鈥淭his makes intuitive sense 鈥撯€� your hands touch everything. It鈥檚 also consistent with how infectious organisms can be spread by hands that touch multiple surfaces.鈥�

Is there anything a person can do to minimize their exposure to flame retardants and plasticizers? 鈥淵es, wash your hands!鈥� Diamond says. 鈥淎lso, wash your cell phone and other handheld electronic devices.鈥� She adds that parents should be careful about giving cell phones to small children, who often put their hands in their mouths and also gnaw on and lick objects rather than using them in the intended manner. 鈥淲e didn鈥檛 collect any data on kids鈥� exposures,鈥� she says, 鈥渂ut it鈥檚 obvious that our results could hold insights into pathways of exposure for them.鈥�

The researchers acknowledge support and funding from , Canada鈥檚 , and the .

The American Chemical 中国365bet中文官网, the world鈥檚 largest scientific society, is a not-for-profit organization chartered by the U.S. Congress. ACS is a global leader in providing access to chemistry-related information and research through its multiple databases, peer-reviewed journals and scientific conferences. ACS does not conduct research, but publishes and publicizes peer-reviewed scientific studies. Its main offices are in Washington, D.C., and Columbus, Ohio.