Omecamtiv mecarbil, a cardiac-specific myosin activator, is being tested for聽. Myosin is present in 鈥渇ast鈥� and 鈥渟low鈥� ATP-hydrolyzing forms; heart disease patients are often deficient in the fast form. Omecamtiv mecarbil binds to both forms to boost ATP hydrolysis and therefore heart function.
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